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chateaujade
Bacteria reproduce rapidly, populations can double in 3 hours or so. So in the span of a day they can double 6 times, that's 64 times original number.

When you take an antibiotic it requires some time to get up to the optimal concentartion in your bloodstream. And it will then kill most of the bacteria rapidly, most but not all. That bunch of survivalist bacteria will then reproduce rapidly, if allowed to. The way to disallow this is to hit them hard and keep on hitting them with massive amounts of antibiotic, so that the tail of the bell curve, the surviving bacteria, is wiped out.

If that does not happen what has occurred is that you have artificially selected the resistant bacteria for survival. That's BAD.

This is precisely why hospitals are chock full of drug resistant bacteria, and quite a few people admitted to hospital die not of their original ailment but of a drug resistant infection acquired in the hospital.

People who truncate their antibiotic regime, cut it short when symptoms disappear, are allowing drug resistant strains of bacteria, the tail of the bell curves, to survive.

And people who take 'preventative' does of antibiotics, are doing the same thing GRATUITOUSLY. This is really really a bad idea.

What do we need, vu-graphs? An intro by C.Everett Koop MD?


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Posted on: 12:57 am on Aug. 24, 2002
osten
Despite taking the usual precautions, I recently contracted chlamydia during my first trip to Thailand (nice welcome gift). Upon returning home, I visited the local clinic, was tested, and found positive for Chlamydia, but negative for everything else. I was prescribed Zithromax, which I took exactly as directed. But, much to my surprise, the infection did not go away.

Upon returning to the clinic, they asked if I had sex with anyone else since returning home because the virus may have just gotten passed back and re-infected me. But, since I did not, this was not possible. They prescribed zithro a second time and, once again, it did not work. So, now I have been prescribed Doxycycline because the doctor thought my body may have a better reaction. On day 4, I still have symptoms, so I am getting a bit nervous now. What can be tried next?

Anyway, the whole point of my post is to provide proof to the antibiotic abusers that they are creating antibiotic-resistant strains by unneccesarily taking antibiotics as a preventive measure. Think about this because it may be you who has this trouble the next time.

osten


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Posted on: 11:08 am on May 20, 2004
hzink
Hi CJ,

While your advice is excellent advice (particularly the one about people cutting short their anti-biotics regimens - that's just plain stupid), an argument can be made for the prophylactic use of certain broadband anti-biotics AS LONG AS DONE UNDER SUPERVISION BY YOUR DOCTOR!!!!

Your advice about self-medicating is correct. Unless you know what you are doing, DO NOT self-diagnose, do not self-medicate. Just because your buddy takes it doesn't mean it will be okay for you. That's a simple rule.

Back to prophylactic use - Malaron, an anti-malaria medication is a good example of a prophylcatic anti-biotic, which I was taking while visiting udonthani. Furthermore, the key with taking a prophylactic antibiotic is to make sure you do not stop prematurely - i.e. you need to take enough to last you beyond the last day of your visit.

Hence, such a use of antibiotics is okay for visits lasting up to 10 days, as long as you can take a 15-20 day supply.

I start 2-3 days before my flight, take it throughout my stay, and maintain the dosage for 5 days after my return. This assures me that all bacteria acquired in a foreign country are eradicated. So far, the only time I have had problems was the one trip I did NOT adhere to that rule.

Things to consider when taking antibiotics, though:

- do NOT take any other medication while you are taking them, unless you cleared it with your doctor. It is never a good idea to mix medications.

- do NOT drink alcohol while taking them (which, I guess, nixes these solutions for 99% of the bros on the forum). as it's simply not a good idea to mix any medication with alcohol. In fact, it's downright stupid.

- stay out of the sun, use heavy sunscreen, and wear sunglasses - some antibiotics will heavily increase your sensitivity to sunlight, and you will get a sun-rash or sunburn much faster.

Otherwise, what CJ said.

Harry


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Posted on: 2:12 pm on May 20, 2004
Smegma
I disagree hzink.

The general medical community consensus is not to take antibiotics as a prevention for the reasons Osten mentions.

For Malaria, it is generally agreed that one should take antimalarial drugs when visiting endemic areas.

BTW, antimalarial drugs are not antibiotics. Malaria is caused by is a parasitic disease -cause by the Plasmodium falciparum parasite- spread by the bites of infected mosquitoes. Whereas antibiotics are are a group of drugs which treat bacterial infections, ranging from quite mild infections to serious, life-threatening diseases.



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Posted on: 2:08 am on May 21, 2004
papa

Quote: from Smegma on 2:08 pm on May 21, 2004

BTW, antimalarial drugs are not antibiotics. Malaria is caused by is a parasitic disease -cause by the Plasmodium falciparum parasite- spread by the bites of infected mosquitoes. Whereas antibiotics are are a group of drugs which treat bacterial infections, ranging from quite mild infections to serious, life-threatening diseases.


In stead of the 'normal' anti-malaria drug (i.e hydroxychloroquine, proguanil, mefloquine) docters can subscribe doxycyclin, especialy in South-east asia where multiple resistent P. falciparum is found.
Hence, anti-malaria can be a antibiotic, but consult ALWAYS a docter because it depends on the place and time you are going to spent your holidays.


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Posted on: 9:22 pm on May 30, 2004
Smegma
Hmmmm.... though you are correct on doxyclyne, I still think the terminolgy would be the other way around. I mean, saying that there is an antibiotic that can also be used as anti-malarial drugs.

For some general info to travellers, this is a decent site:

http://www.traveldoctor.co.uk/malaria.htm

Papa, are you German?


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Posted on: 4:49 am on May 31, 2004
     

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